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Reccurence plot for heart rate variability analysis
Franěk, Pavel ; Čmiel, Vratislav (referee) ; Janoušek, Oto (advisor)
The aim of this thesis is to describe the variability of cardiac rhythm and familiarity with the methods of the analysis, ie by monitoring changes in heart rhythm electrogram signal recording and using the methods in the time domain using recurrent diagram. The work describes the quantification of the methods and possibilities of quantifiers in the evaluation of heart rate variability analysis. It also describes the clinical significance of heart rate variability and diagnostic capabilities changes of heart rate variability caused by ischemic heart disease. The practical part describes how to create applications in Matlab to calculate the quantifiers analysis of heart rate variability in the time domain using recurrent diagram. The calculation was made of the positions R wave elektrogram signal isolated rabbit hearts. The calculated values of quantifiers both methods were statistically evaluated and discussed.
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Experimental models of ischemic brain injury
Alexová, Daniela ; Valeš, Karel (advisor) ; Alterová, Kateřina (referee)
Title: Experimental models of ischemic brain injury Author: Daniela Alexová Department: Department of Physiology Supervisor: RNDr. Karel Valeš, Ph.D. Abstract: This bachelor thesis focuses on the experimental models of ischemic brain injury closely related to one of the most common forms of brain damage, the ischemic stroke. This type of brain injury is connected to subsequent serious neurological deficits. The studies of experimental models of ischemic brain injury are therefore essential for primary and secondary research. The first two parts of the thesis are dedicated to brief characterization of stroke with focus on types of stroke, incidence, risk factors and molecular mechanism of injury. Next part summarizes the challenges of experimental modeling of ischemic brain injury and the specifics of small and big laboratory animals. The core of the thesis is the description of 11 most frequently used models. Selected models were divided into focal and global models and in each of these categories were furthermore characterized according to procedural performance, animal mortality or success of lesion induction. The key modifications of models introduced during the years in order to increase the reproducibility of brain injury are described as well. All 11 selected experimental models are summarized at the...
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Reccurence plot for heart rate variability analysis
Franěk, Pavel ; Čmiel, Vratislav (referee) ; Janoušek, Oto (advisor)
The aim of this thesis is to describe the variability of cardiac rhythm and familiarity with the methods of the analysis, ie by monitoring changes in heart rhythm electrogram signal recording and using the methods in the time domain using recurrent diagram. The work describes the quantification of the methods and possibilities of quantifiers in the evaluation of heart rate variability analysis. It also describes the clinical significance of heart rate variability and diagnostic capabilities changes of heart rate variability caused by ischemic heart disease. The practical part describes how to create applications in Matlab to calculate the quantifiers analysis of heart rate variability in the time domain using recurrent diagram. The calculation was made of the positions R wave elektrogram signal isolated rabbit hearts. The calculated values of quantifiers both methods were statistically evaluated and discussed.
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